Course Description

Course Fee: $255

This three-module course presented by Dr. James Greenblatt presents a novel paradigm for the prevention of Alzheimer’s, as well as general cognitive decline. It examines the pathophysiology of neurodegenerative illness from a functional medicine and systems biology framework, focusing on biochemical abnormalities contributing to neuronal dysfunction that are modifiable at certain prodromal stages…and, accordingly, viable functional treatment targets. Research supporting the use
of low-dose lithium and other evidence-based nutritional interventions as part of a preventative approach will be objectively reviewed, and the mechanisms through which these interventions confer neuroprotection elucidated.

Finally, evidence-based recommendations for the use of low-dose lithium and other functional medicine treatments will be proffered, providing students with actionable information that can be incorporated into existing treatment protocols to maximize therapeutic – and cognitive – outcomes.

Learning Objectives

Upon completion of this course, students will be able to:

  • Describe one way in which high homocysteine is related to risk for Alzheimer’s
  • List three OPCs and describe how they may impact brain health
  • Explain what each of the letters in the ZEEBRA model stands for, as an approach to treating Alzheimer’s and cognitive decline

Course curriculum

    1. Alzheimer’s Disease and Cognitive Decline-1

    2. ALZ_Cog Decline MODULE 1 HANDOUT

    1. Alzheimer’s Disease and Cognitive Decline-2

    2. ALZ_Cog Decline MODULE 2 HANDOUT

    1. Alzheimer’s Disease and Cognitive Decline-3

    2. ALZ_Cog Decline MODULE 3 HANDOUT

    1. ALZ_Cog Decline COURSE BIBLIOGRAPHY

    2. Hara.17. Evaluation of the Neuroprotective Potential of N-Acetylcysteine for prevention of cognitive aging and dementia

    3. Jayedi.18. Vitamin D status and risk of dementia and Alzheimer’s disease_a meta-analysis of dose-response

    4. Alam.17. Vitamin B12 offers neuronal cell protection by inhibiting Aβ-42 amyloid fibrillation

    5. Smith et al.18. Homocysteine and Dementia_An International Consensus Statement

    6. Small. 18. Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults

    7. Wang. 09. Consumption of Grape Seed Extract Prevents Amyloid-Beta Deposition and Attenuates Inflammation in Brain of Alzheimer's Mouse

    8. Greenblatt.19. Alzheimers redefined_nutritional lithium as the foundation for prevention

About this course

  • $255.00
  • 14 lessons
  • 2.5 hours of video content

Course Faculty

James Greenblatt, MD

Founder, Chief Medical Officer

Dr. James Greenblatt is a globally recognized pioneer in functional and integrative psychiatry with over 30 years of clinical experience. He has dedicated his career to transforming the treatment of mental health disorders through precision-based approaches that integrate laboratory testing, nutritional interventions, and root-cause analysis. Dr. Greenblatt earned his medical degree and completed a psychiatry residency at George Washington University, and pursued a Child and Adolescent Psychiatry fellowship at Johns Hopkins Medical School. A prolific author, Dr. Greenblatt has written eight books, including the bestseller Finally Focused: The Breakthrough Natural Treatment Plan for ADHD. He serves as an Assistant Clinical Professor of Psychiatry at Tufts University School of Medicine and Dartmouth College’s Geisel School of Medicine. Previously, he served as Chief Medical Officer for Walden Behavioral Care/Monte Nido, a national mental health organization specializing in eating disorders. In 2019, Dr. Greenblatt founded Psychiatry Redefined, a leading platform for continuing education for clinicians in functional and integrative psychiatry, designed to bridge critical knowledge gaps for mental health professionals. His innovative work combines evidence-based research with decades of clinical expertise in functional and integrative psychiatry to promote personalized, precision medicine approaches for sustainable mental health outcomes. in 2024, Dr. Greenblatt founded Mind Refined, a consumer education platform in functional and integrative approaches to mental healthcare. Dr. Greenblatt lectures internationally on nutritional psychiatry and functional medicine’s transformative role in treating mental illnesses.